本文由 泡泡拔 翻譯於PWCCA網站 http://www.caninegeneticdiseases.net/dm/index.html
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圖為美國有柯基DM病例的各州
什麼是退化性脊髓神經病變(DM)?
Degenerative myelopathy (DM) is a progressive disease of the spinal cord in older dogs. The breeds most commonly affected include German Shepherds, Welsh Corgis, Irish Setters, and Chesapeake Bay Retrievers. The disease has an insidious onset typically around 9-11 years of age. It begins with ataxia: a loss of coordination in the hind limbs. The affected dog will wobble when walking, knuckle over or drag their feet, and may cross the feet. As the disease progresses, the limbs become weak and the dog begins to buckle at the knees and have difficulty standing. The weakness gets progressively worse until the dog is unable to walk. They may ultimately lose continence and function in the front limbs.
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